Wed, 25 May 2022

Seoul [South Korea], May 12 (ANI/Global Economic): NeoImmuneTech said on the 11th that it has obtained the approval for a phase 2 clinical trial plan that concomitant administration of US Merck's immune checkpoint inhibitor Keytruda and its T-cell amplifier NT-I7 to patients with glioblastoma from the United States FoodDrug Administration (US FDA).

The phase 2 trial will be led by Professor Jian Campian at the US Mayo Clinic. It will evaluate the safety and treatment efficacy. Merck and NeoImmuneTech will supply Keytruda and NT-I7.

The research team expects the concomitant administration of Keytruda and NT-I7 to improve the survival rate of patients with glioblastoma.

The survival time of glioblastoma is less than 6 months, and the prognosis is very poor. Some chemotherapy drugs and a target anticancer Avastin are used for treatment, but the effectiveness is not significant. Genexine is conducting a clinical trial of the concomitant administration of Avastin and Efineptakin Alfa (GX-I7) in Korea, and NeoImmuneTech plans to test immune checkpoint inhibitor and T-cell amplifier. After the phase 2 trial, it will enter the phase 3 trial of the most likely treatment.

NT-I7 is a drug that amplifies T cell immunity to remove cancer cells and infected cells. Currently, it is under clinical development to treat various deadliest cancers and infectious diseases. (ANI/Global Economic)

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